Best Isekai Anime To Watch If You Like Possibly the Greatest Alchemist of All Time

In the ever-expansive world of isekai, stories about protagonists desiring a quiet life away from conquests and battles have become all too common. Possibly the Greatest Alchemist of All Time starts off in this direction, but as the main character unknowingly chooses the most powerful skill, his journey evolves into a complex path filled with possibilities.

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The exciting tale captures the essence of transformation, highlighting the challenges that come with great power while staying true to one's values. Here are the best isekai anime like Possibly the Greatest Alchemist of All Time for the fans of the series who wish to experience a similar blend of self-discovery, heartwarming moments, and adventure.

7 That Time I Got Reincarnated as a Slime

A Series About Shaping Destiny and Embracing Life's Challenges

After the ordinary office worker Satoru Mikami succumbs to an incident of senseless violence, he is reincarnated in a fantasy world as a goop of slime. With the ability to imitate the power of anything he devours, he undergoes a dramatic transformation that not only alters his fate but also the fortunes of his new world.

That Time I Got Reincarnated as a Slime, like Possibly the Greatest Alchemist of All Time, is an exciting isekai series that focuses on an overpowered protagonist who embarks on life-changing adventures and uses his newfound powers wisely to reshape the world. Both anime revolve around themes like personal growth, creating lasting change, and making the most of unexpected challenges in life.

6 By the Grace of the Gods

A Show About Second Chances

By the Grace of the Gods recounts the story of Ryouma Takebayashi, a child blessed by gods to savor the wonders of life after having endured a harsh and lonely existence in his last life. Although he spends a few years enjoying solitude away from civilization, following a series of events, he eventually embarks on a journey beyond his home. Like Iruma, Ryouma's adventures are fulfilling and lead to meaningful connections that transform his life.

5 The Rising of the Shield Hero

Tale of an Otaku Who Became a Savior

Naofumi Iwatani is an otaku who is one of the Four Cardinal Heroes selected from modern-day Japan to save the Kingdom of Melromac in an alternate universe. But soon after arrival in the new world, things go south for the young hero as he is regarded as the weakest by his peers for being bestowed with just a shield, and to make matters worse, he is later falsely accused of assault, following which he falls out of favor with the public.

The Rising of the Shield Hero follows Naofumi as he sets out to redeem himself and fulfill his duty as a hero, despite being shunned by society. Anime fans who enjoy Possibly the Greatest Alchemist of All Time will find The Rising of the Shield Hero appealing, as it follows Naofumi’s journey to overcome adversity, build alliances, and grow into an almost invincible hero, much like Takumi.

4 Death March to the Parallel World Rhapsody

Story of a Programmer Stuck in the Game World

Death March to the Parallel World Rhapsody might interest Possibly the Greatest Alchemist of All Time fans who are looking for an isekai series with an overpowered protagonist. The show revolves around a programmer named Ichirou Suzuki, who mysteriously gets transported to a fantasy RPG world.

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There, Suzuki learns that he has been imbued with the powers of a high-level adventurer capable of embarking on epic adventures and winning epic battles against fearsome foes. Thrilled to experience what his new life has to offer, Ichirou sets out to explore the magical world with all its wonders and dangers.

3 Farming Life in Another World

Isekai Series About a Terminally Ill Man Who Received God's Blessing

Kinosuke Naito's Farming Life in Another World is a story of an average man whose untimely death moves god into gifting him another chance at living on his own terms. Bestowed with Almighty Farming Tool, he is reincarnated in another world, where he uses his newfound powers to cultivate a peaceful and fulfilling life. Just like Takumi Iruma, the protagonist finds meaning and a renewed zest for life by using his abilities for the greater good, all the while transforming the fortunes of people around him in the process.

2 Campfire Cooking in Another World with My Absurd Skill

The Tale of a Salaryman Who Was Chosen as a Hero

Tsuyoshi Mukouda is an ordinary salaryman whose life takes a dramatic turn when he is summoned to another world as a hero. Gifted with the bizarre skill known as Online Supermarket, Mukouda soon seems like an inappropriate candidate to lead combat efforts for the Kingdom of Reijseger. However, his powers eventually prove invaluable as he uses them to bring luxurious utensils from Japan. Tsuyoshi's delicious dishes soon earned him recognition and allowed him to make a contract with the mythical wolf Fel.

As Mukouda's fate takes an unprecedented turn, he takes advantage of his circumstances to embark on adventures around the world. If you like Possibly the Greatest Alchemist of All Time and wish to watch another isekai anime where the main character uses an unconventional skill to thrive in a fantasy world, then you should consider adding Campfire Cooking in Another World with My Absurd Skill to your watchlist.

1 A Journey Through Another World: Raising Kids While Adventuring

Story of an Unlikely Adventurer

Like Takumi Iruma from Possibly the Greatest Alchemist of All Time, Takumi Kayano is transported to a fantasy world after an accidental mishap involving the god of wind, Silphyleel. Gifted with newfound powers, Kayano is spawned in the dangerous Forest of Gaia. There, he meets and befriends five-year-old twins Allen and Elena, whose extraordinary physical strength defies logic.

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By  Oluwatokiloba Folami

Unaware of what the fantasy world has in store for them, the trio embarks on a grand adventure that not only changes their lives but also dramatically alters the destiny of the world they inhabit. A Journey Through Another World: Raising Kids While Adventuring is an exciting isekai series, much like Possibly the Greatest Alchemist of All Time, featuring protagonists who, despite being victims of mishaps, turn their circumstances into opportunities for growth and adventure.

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Possibly the Greatest Alchemist of All Time

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TV-14

Animation

Sci-Fi & Fantasy

Action & Adventure

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Release Date

2025 - 2025

Network

Tokyo MX

Directors

Kyohei Suzuki

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Cast

See All

• 
  Shogo Sakata

  Takumi Iruma (voice)
• 
  Ai Kayano

  Sofia Sylphid (voice)
• 
  Nao Toyama

  Maria (voice)
• 
  Afumi Hashi

  Maple / Kaede (voice)

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Studio

Studio Comet

Creator

Kogitsunemaru

Streaming Service(s)

Crunchyroll

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