Summary
- Jack Krauser is a challenging boss in Resident Evil 4 with intense Quick-Time Events.
- Jack Baker in Resident Evil 7 has players engage in a thrilling chainsaw fight.
- Mother Miranda is a climactic final boss in Resident Evil Village, leading to a satisfying conclusion.
Resident Evil bosses run the gamut from giant mutated animals like snakes and crocodiles to humans who have injected themselves with one too many viruses. There have been a lot of wild boss interactions since the series started in 1996, and not all of them are satisfying to beat on a cosmic level.
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Other boss fights are, for one reason or another, which could include everything from stopping a villain from being smug to the encounter itself being hard. There's nothing like pulling out a victory after several attempts in Resident Evil games. Let’s go through the entire series and rank the most satisfying Resident Evil bosses to take down.
Spoilers Ahead for the Resident Evil series
6 Jack Krauser (Resident Evil 4)
Comrades Become Bitter Rivals
Resident Evil 4
- Released
- January 11, 2005
WHERE TO PLAY
- ESRB
- M for Mature: Blood and Gore, Intense Violence, Language
- Genre(s)
- Survival Horror
Jack Krauser was introduced in Resident Evil 4 as a longtime partner of Leon S. Kennedy before he betrayed the military. He is a constant thorn in Leon’s side throughout the game, hampering his mission to save the President’s daughter. The original 2005 version of the Krauser boss fight had multiple Quick-Time Events, and they are some of the hardest moments to pull off in the game.
The 2023 remake makes these encounters easier, and the final encounter with Krauser is overall a bit simpler. For a real thrill, players should remember how satisfying it was to wipe the smirk off Krauser’s face in that final duel. It’s a long boss fight, almost like it was taken out of a Metal Gear game, with Krauser constantly on the move.
5 Jack Baker (Resident Evil 7: Biohazard)
It’s A Chainsaw Fight!
Resident Evil 7: Biohazard
- Released
- January 24, 2017
WHERE TO PLAY
- ESRB
- Mature 17+ / Blood and Gore, Intense Violence, Strong Language, In-Game Purchases
- Genre(s)
- Survival Horror, Psychological Horror, First-Person
There’s another tough Jack in the series, Jack Baker, who was introduced in Resident Evil 7: Biohazard. The game begins with protagonist Ethan Winters arriving at an old house in the Deep South while searching for his missing wife. He then gets kidnapped by the Baker family, terrorized beyond repair, which involves his hand getting chopped off.
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Players will go through the game dealing with each family member, and Jack is the first one they'll take down permanently. He will constantly stalk players in the early game, even busting through walls. What makes this final encounter with Jack interesting is that it ends with a chainsaw fight to the death. It’s thrilling and satisfying when those blades cut deep through Jack’s mutated body.
4 Mother Miranda (Resident Evil Village)
Give Me Back My Daughter!
Resident Evil Village
- Released
- May 7, 2021
WHERE TO PLAY
Mother Miranda is the final boss of Resident Evil Village, and it’s a big climactic fight, which this series is always good at building towards. She’s a manifestation of the evil sludge that Ethan initially encountered in Resident Evil 7: Biohazard, although it goes deeper than that. Besides the spectacle being great, the most memorable part is defeating Mother Miranda because it saves Ethan’s daughter, Rose, in the process.
Far more messed up than his previous adventure of being stalked by the Bakers, Resident Evil Village is about Ethan collecting jars of Rose’s body across a sprawling haunted town somewhere in Europe. It doesn’t really make sense how Rose could live after being dissected and scattered, but realism has never been the point of the series.
3 Ramon Salazar (Resident Evil 4)
A Pint Sized Dictator
Ramon Salazar is another villain from Resident Evil 4, and he’s just pure evil, unlike Krauser, who was once good before being corrupted. Salazar is a tiny man talking a big game, but only because he thinks he holds all the cards. His voice is slimy, and his complexion isn’t much better, like some sort of ghostly Spanish goblin.
That’s why it’s hilarious whenever Leon gets the drop on him in their encounters, like when he throws a knife through Salazar’s hand. Watching the villain squirm is satisfying beyond belief, and it gets better after his boss fight. The original game’s depiction of Salazar is better, giving players more room to hate on this Saturday Morning Cartoon villain, but the 2023 remake has a good Salazar sequence as well.
2 Nemesis (Resident Evil 3 2020)
Stalker No Stalking
Resident Evil 3
- Released
- April 3, 2020
WHERE TO PLAY
- ESRB
- M for Mature: Blood and Gore, Intense Violence, Strong Language
- Genre(s)
- Horror
Resident Evil 2 was the first game to introduce an enemy that would follow players around the map in Mr. X. However, Mr. X only appeared randomly and in very specific situations, which were dialed up in the 2019 remake. This idea was expanded in Resident Evil 3: Nemesis by adding the Nemesis mutant to chase Jill Valentine around Raccoon City.
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Like the 2019 remake of Resident Evil 2, this game’s 2020 remake—simply titled Resident Evil 3— made Nemesis’ presence more domineering. That’s why the remake makes Nemesis’ final boss fight and eventual takedown so much more satisfying, especially because Jill’s weapon is a gigantic rail gun that looks like something a mech would use. It’s a great final moment, and overall, while Nemesis is annoying to deal with, it’s a great and memorable villain in the series.
1 Albert Wesker (Resident Evil 5)
Breaking Those Sunglasses At Long Last
Resident Evil 5
- Released
- March 5, 2009
WHERE TO PLAY
- ESRB
- M for Mature: Blood and Gore, Intense Violence, Strong Language
- Genre(s)
- Survival Horror
Albert Wesker was a member of S.T.A.R.S., the elite police unit from Raccoon City. He appeared in the first game along with Jill and Chris Redfield, who were the two playable protagonists. It was a twist to find out that Wesker was actually an agent of Umbrella, and he continued to be a nuisance to characters throughout the series, especially whenever Chris or his sister, Claire, appeared in a game.
No matter what they did to him, Wesker kept popping up, which made him a great villain to despise over time. At long last, though, players got to deal with Wesker once and for all in Resident Evil 5 in one of the most over-the-top boss fights not just in the series, but in video games as a whole. It involved fighting his mutated form in an active volcano, and Chris punching boulders like The Hulk, which was overall a downright goofy masterpiece of a scenario.
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