Vex the Siren in Borderlands 4 has some truly broken builds, and one of them uses the Incarnate Skill from the green skill tree. If players want an OP Siren build in Borderlands 4, then they will want to invest in these skills and the gear listed below. This build is designed around Vex being a true damage-dealing monster, who is able to absolutely shred through bosses and enemies deep into Ultimate Vault Hunter Rank 5 with stacking damage multipliers from Critical Hits and Kinetic Damage weapons.
Best Skills for Incarnate Vex
|
Skill |
Description |
Why It's Useful |
|---|---|---|
|
Leeching Attunement (1/5) |
Attunement Skill. While Vex is Attuned to Kinetic, she gains Lifesteal and increased Reload Speed. These effects persist for a Duration after Attunement is switched. |
This makes Kinetic weapons more effective by allowing Lifesteal and Reload Speed bonuses. |
|
Grave Sights (5/5) |
Kill Skill. Vex gains increased Critical Hit Damage and Gun Handling. |
This allows Critical Hit Damage to stack on kills, providing an increase to damage and handling. |
|
Bloodletter (5/5) |
Gun and Skill Critical Hits have a chance to apply Bleed, causing Kinetic Status Effect Damage over time for a Duration. Bleed is affected by Status Effect Application Chance, and is itself considered a Status Effect. |
A Critical Hit has a chance to apply Bleed, which causes more Kinetic Damage over time, with a max stack of 20, providing an immense amount of damage. |
|
Grave Implements (5/5) |
Kill Skill. Vex and her Minion(s) gain increased Gun Damage for a Duration. |
A +20% increase to Gun Damage with a max of 3 stacks will help build Vex's damage numbers. |
|
Material Components (4/5) |
Vex gains increased Kinetic Damage and Kinetic Status Effect Damage. |
More Kinetic Damage is great, but Kinetic Status Effect Damage will boost Bleed even more. |
|
Grave Power (3/3) |
Vex's Kill Skill gain increased Max Stacks. |
More Max Stacks, means more overall damage on Kill Skills, almost doubling some skills. |
|
Witchy Trigger Finger (Augment) |
Dealing Damage with Eldritch Blast or Phase Explosion will fully Refill Ammo of Vex's current Gun, and grants a stack of Witchy Trigger Finger, increasing Gun Damage for a Duration. Stacks of Witchy Trigger Finger persist even after Incarnate ends. |
Using the Action Skill will not only deal immense damage and fully heal Vex, but it will now reload her weapon and grant extra Gun Damage when the Action Skill causes any damage. |
|
Drink Full (5/5) |
Whenever Vex deals Gun Damage, she gains a Stack of Drink Full, increasing her Fire Rate. Stacks of Drink Full are lost if a new Stack has not been gained for a Duration. |
Increases Fire Rate with a Max Stack of 50, meaning a 30% increase to Fire Rate. |
|
Mortal Terror (5/5) |
Chance to Activate Kill Skills when Critically Hitting enemies. |
Shooting enemies in their Critical Hit spots means that you can gain Kill Skill Stacks without killing enemies, perfect for boss fights with little ads. |
|
Vibe Check (Capstone) |
Eldritch Blast is now a Charge Skill (3) Activating Eldritch Blast consumes all Charges to Ricochet on hitting an enemy. Will Ricochet once for each Charge consumed. Eldritch Blast's Cooldown reduction from Gun Damage is doubled |
Vex's Action Skill recovers faster with Gun Damage, and it can now be fired at enemies from range. |
|
Strike Me Down (1/1) |
Whenever Vex would enter Fight For Your Life, she immediately gets a Second Wind, becomes Invisible for a Duration, and causes a Phase Explosion. |
This is a get out of jail free card every 120 seconds, and the damage from Phase Explosion is great. |
|
Sanguine Fiends (1/5) |
Kill Skill. Vex and her Minion(s) restore Health. |
Killing enemies, or activating a Kill Skill from Mortal Terror, immediately regains a portion of HP. |
|
Cold Iron (5/5) |
Vex gains increased Gun Damage. |
The more Gun Damage, the merrier. |
|
Portents of Suffering (3/5) |
Vex and her Minion(s) gain increased Status Effect Damage. |
More Status Effect Damage directly impacts the Bleed damage of Kinetic Damage for even more powerful shots. |
|
Grave Assault (1/5) |
Kill Skill. Vex and her Minion(s) gain increased Fire Rate for a Duration. |
This is an additional 9% to Fire Rate thanks to Grave Power, meaning players will nearly double their total Fire Rate. |
|
Grave Fiends (5/5) |
Kill Skill. Vex and her Minion(s) deal increased Damage. |
More Damage Dealt per Kill Skill, and with Grave Power, that's a total of +70%. |
For this Vex Incarnate build, players are going to be investing heavily into the Vexcalation skill tree for a multitude of reasons. Players will want to invest in Kill Skills for increased stats with Fire Rate and Gun Damage, but most importantly, they need the Bloodletter skill. This build relies on the Bloodletter skill as it has a chance to apply Bleed on Critical Hits, which provides additional Kinetic Status Effect Damage. This Critical Hit damage can be multiplied into the billions by constantly re-applying Critical Hit damage. For this build to work, you will want to use a Throwing Knife Ordnance with the Penetrator Augment to make anywhere on the target a Critical Hit. Then, unload ammo into them and let the Bleed stack, and throw the Knife Ordnance to reapply more critical hit damage. This can be repeated on every enemy to annihilate bosses and destroy standard enemies, even without the Throwing Knife.
Best Weapons and Gear for Incarnate Vex
There are two main focuses of Vex's Incarnate build: Kinetic Energy weapons and Throwing Knife Ordnance. Players should use their own preference of primary weapons, but we'd recommend farming Axemaul, located at The Toil of Spoiling Vis Auger Mine in Carcadia District, Dominion. This boss can drop Armored Bod, a Legendary Shotgun with the following effect: Counts as a Shotgun, Assault Rifle, Sniper Rifle, Pistol, and an SMG. This range of weaponry stacks wonderfully with Vex's damage skills.
For Ordnance, a Throwing Knife is essential to get this build into OP status. Not just any Throwing Knife will do, as players will need to look for one with Penetrator Augment, which will make any damage to the target a Critical Hit, no matter where you are aiming. This is the essential perk to make the build work, but Damage AMP Payload is also good, as it increases the target's damage taken.
For Repkits and Class Mods, try to focus on ones that provide decent stat advantages, like a buff to health, Elemental Affinity, or simple Damage Buffs. When it comes to Shields, just use whatever you are comfortable with. For Enhancements, focus on Critical Damage and Weapon Damage upgrades.
Best Specializations for Incarnate Vex
|
Specialization |
Perk |
|---|---|
|
Brute (20) |
Riddle You This |
|
Sharpshooter (10) |
In The Zone |
|
Killer (10+) |
Contamination Compounding Afflictions |
Vex Incarnate's most important Specializations are Brute and Sharpshooter. Players will want to get Brute to 20, which passively increases Gun Damage, but also features a vitally important skill: Riddle You This. With this skill, players can gain additional Gun Damage by dealing damage, which stacks to 50, granting another 50% total damage buff. After, invest into Sharpshooter for increased Reload Speed and Accuracy, but only for 10 points to get In The Zone to increase Gun Damage and Critical Hit Damage while aiming. With the remaining points, invest heavily into Killer for an increase to Critical Hit Damage and Status Effect Damage, and grab Contamination for an increased Status Effect Application Chance on Critical Hits, and Compounding Afflictions for an increase to Damage based on the Status Effects applied.
Best Firmware for Incarnate Vex
|
Firmware |
Bonuses |
Slots |
|---|---|---|
|
Deadeye |
Gun Accuracy is increased by +30% Gun Critical Damage is increased by +25% Every Critical Hit grants 15% Critical Damage per Stack (for a Maximum 5 Stacks) for 10s |
3 |
|
Oscar Mike |
Gun Reload Speed is increased by +10% Gun Damage is increased by up to +20% based on the emptiness of your Gun's Magazine |
2 |
The most essential Firmware for this build is Deadeye, as with all 3 pieces equipped, that's more Gun Accuracy and more Gun Critical Damage to really boost the total damage output. This also provides more damage from Critical Hits. For the next bonus, it's really your choice, but we went for Oscar Mike so we could have more Gun Damage and Gun Reload Speed for intense situations.
Borderlands 4
-
OpenCritic Reviews
- Top Critic Avg: 82 /100 Critics Rec: 88%
- Released
- September 12, 2025
- ESRB
- Mature 17+ / Blood and Gore, Intense Violence, Sexual Themes, Strong Language, In-Game Purchases, Users Interact
- Developer(s)
- Gearbox Software
- Publisher(s)
- 2K
